Journal of Liver Cancer

Boo Sung Kim

1 Article

Four Cases of Hepatocellular Carcinoma Treated with CyberKnife: So Yeon Lee, Si Hyun Bae, Min Su Kim, Jeong Won Jang, Jong Young Choi, Seung Kew Yoon, Joon Yeol Han, Kyu Won Chung, Young Nam Kang, Byung Ock Choi, Ihl Bohng Choi, Boo Sung Kim; Journal of the Korean Liver Cancer Study Group. 2005;5(1):30-36. Published online June 30, 2005

Abstract PDF: CyberKnife, a new FSRT (Fractionated Stereotactic Radiotherapy) system which utilize a novel, light-weight, and high-energy radiation source, was introduced as a newly-developed therapeutic modality for solid tumors. In this report, we present 4 cases of hepatocellular carcinoma treated with CyberKnife. - 1. Single nodular hepatocellular carcinoma (stage II), 2. Advanced hepatocellular carcinoma with portal vein invasion (stage IVa), 3. Advanced hepatocellular carcinoma with metastatic intraabdominal lymphadenopathy (stage IVa), 4. Advanced hepatocellular carcinoma with right atrium invasion (stage IVb). Two patients showed complete response, and the other two patients showed partial response without major complications. After the treatment, they are in good general condition under observation at out-patient clinic. The present cases show that CyberKnife can give a chance of cure for small hepatocellular carcinoma and may also be used as an additional therapeutic modality for advanced hepatocellular carcinoma.

Boo Sung Kim

3 Articles

A Case of Hepatocelluar Carcinoma Mimicking Focal Nodular Hyperplasia: Eui Ju Park, Jae Young Jang, Soung Won Jeong, Sae Hwan Lee, Sang Gyune Kim, Young Seok Kim, Hong Soo Kim, Boo Sung Kim, So Young Jin, Ji Young Hwang; Journal of the Korean Liver Cancer Study Group. 2014;14(1):53-59. Published online March 31, 2014; DOI: https://doi.org/10.17998/jlc.14.1.53

Abstract PDF: Recently, detection of an incidental hepatic tumor has rapidly increased with the introduction of multi-modality imaging techniques. And then, it is very important to determine whether these tumors are malignant or benign lesions. In some cases, differentiation from other hepatic tumors such as focal nodular hyperplasia or hepatic adenoma and hepatocellular carcinoma can be extremely difficult, both clinical and radiologic finding. Therefore, it is suggested that combination of multi-modality imaging study than using only a single imaging test. Despite advanced imaging studies such as computed tomography (CT), magnetic resonance imaging (MRI), contrast enhanced ultrasonography, and positron emission tomography (PET) showed a high sensitivity and specificity, role of liver biopsy is still remained to confirm the diagnosis. The use of liver biopsy in the diagnosis of hypervascular hepatic tumors is controversial. However if the tumors was shown rapid growth tendency and heterogeneous radiological appearance, liver biopsy or surgical resection should be considered to provide final diagnosis and prompt curative treatment. We report a case of a hepatocelluar carcinoma showing similar radiologic characteristics to focal nodular hyperplasia in patients without high risk factors of hepatocelluar carcinoma.

A Case of Advanced Hepatocellular Carcinoma with Portal Vein Thrombosis Treated by Intra-arterial Chemotherapy and Radiotherapy: Sang Gyune Kim, Young Seok Kim, Jae Young Jang, Su Jin Hong, Bong Min Ko, Chang Beom Ryu, Jong Ho Moon, Moon Sung Lee, Chan Sup Shim, Boo Sung Kim; Journal of the Korean Liver Cancer Study Group. 2007;7(1):94-97. Published online June 30, 2007

Abstract PDF: Advanced hepatocelluar carcinoma (HCC) with portal vein thrombosis has a poor prognosis due to inadequate tumor response. 1 year survival rate and median surviral of stage IVa is less than 20%, 3 months respectively. Transarterial chemoembolization (TACE) was known to prolong the overall survival rate in patients with moderately advanced HCC. But, only small number of patients with stage IVa can receive the TACE. Other treatment modalities to manage for advanced HCC are systemic chemotherapy, hepatic arterial infusion chemotherapy or radiotherapy. Especially concurrent chemo-radiotherapy would be a better treatment option. We report a case of good response after repeated hepatic arterial infusion chemotherapy and radiotherapy for patient in advanced HCC with portal vein thrombosis.

A Case of Hepatocellular Carcinoma with Lung Metastasis Treated with Transarterial Chemoembolization: Gab Jin Cheon, Yun Soo Kim, Joon Seong Jung, Young Seok Kim, Jong Ho Moon, Young Deok Cho, Moon Sung Lee, Chan Sup Shim, Boo Sung Kim; Journal of the Korean Liver Cancer Study Group. 2001;1(1):122-126. Published online June 30, 2001

Abstract PDF: A 54 year-old male patient was transferred from pulmonologic division to evaluate hepatic mass incidentally found on chest CT scan. Thirteen years ago, he had been diagnosed as a hepatitis B virus carrier. HBs Ag was positive, and AFP was 118.09 ng/ml. On admission, Chest PA showed multiple variable sized nodular opacities in both lungs. Ill defined inhomogeneous enhanced mass was found at liver dome with multiple metastatic lesions on chest CT scan. Hepatic angiogram showed multiple, abnormal tumor staining on liver dome and nearly entire hepatic segments. After the 2nd TACE using mytomycin C, lipiodol and gelform, previously noted hematogeneous metastatic nodules in both lungs disappeared and volume of liver mass was decreased dramatically and AFP was normalized.